As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.

Diabetes and Obesity affect almost 400 million people worldwide and forecasts anticipate an increase of at least 20% by 2030.

Epidemiological studies have shown a high degree of genetic predisposition and familial aggregation in both diabetes and obesity. Nevertheless, lifestyle interventions have proven valuable in disease prevention and management.

The group of Environmental Epigenetics at the Institute of Experimental Genetics of the Helmholtz Zentrum München is looking for a Postdoc in Experimental Single-Cell biology for an initial period of two years. We are studying mechanisms of parental control of offspring development and health including epigenetic inheritance.
Aim of this project is to use single-cell biology to track germ-cells and maternal tract (uterus, placenta) epigenome reprogramming induced by environmental challenges and parental genetics.

PostDoc Position - Experimental Single-Cell Biology - Environmental Epigenetics Group (m/f/d) 2019/0384

Your tasks

You will use the mouse as a model system and perform droplet-based single-cell RNA and ATAC-Sequencing using the technology established by 10XGenomics and have the possibility to introduce and develop spatial transcriptomics and epigenomics as well. You will be expected to perform computational analysis of the data with available methods.

The ideal candidate brings

  • PhD in Life Science, Natural Science, or comparable
  • Strong background in basic Molecular Biology techniques
  • Background in (single-cell) omics
  • Specific knowledge of gametogenesis and metabolic physiology
  • Profound interest in epigenetics and metabolism
  • At least one first author paper in an international peer-reviewed journal
  • fluency in English

We are looking for a motivated team player with strong communication skills and the desire to work in a dynamic environment. Your desire to understand biological problems is a must and prior experience in the field of epigenetics and/or metabolism is a strong plus.

What we offer you

A challenging and versatile field of work providing you with the freedom to follow your instinct and be creative. With the help of extensive and goal-orientated professional development measures and career-building programmes we encourage you to grow as a person. To ensure a good work/life balance we assist you with flexible working hours, in-house health management, a nursery, and an “Elder Care” concept as well as other consultation and support options.

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and research institutes it offers an intellectually stimulating environment.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (TV EntgO Bund).

The position is (initially) limited to two years, but under certain circumstances an extension can be arranged.

The activity involves special knowledge and experience specific to own scientific skills.

As a holder of the Total E-Quality Award, we promote equality of opportunity. Applications from women are welcome. Qualified applicants with physical disabilities will be given preference.

Curious? If you have further questions, simply contact Dr. Raffaele Teperino on 089 3187-3079, who will be happy to be of assistance.

Dr. Raffaele Teperino

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Experimental Genetics
Ingolstädter Landstraße 1

85764 Neuherberg bei München

The Helmholtz Zentrum München is part of the Helmholtz Association, Germany's largest scientific organization. Altogether 40 000 people currently work in its 19 scientific-technical and biological-medical research centers. The Association's annual budget amounts to around 4.7 billion Euros.